A New Foundation for Genomics

Our mission is to provide for academia and industry a foundation DNA language model capable of predicting phenotypic features across scales — from gene expression profiles to high-level organism traits.

Our model is designed to empower scientific research and drive innovations in biotechnology and molecular medicine.

create your own block from scratch

Gene therapy involves delivering functional gene copies into human cells to restore or enhance molecular functions. This therapy requires precise control over where and how much a gene is expressed in the body. DNA language models assist by predicting gene expression levels in specific cell types, enabling the design of synthetic promoters that ensure high expression in target cells while minimizing expression in off-target tissues. This improves both the safety and effectiveness of gene therapy treatments.

create your own block from scratch

The platform uncovers the effects of non-coding variants on gene expression, distinguishing pathogenic from benign mutations. This application enhances molecular diagnostics, risk prediction, and understanding of disease mechanisms, ultimately improving patient outcomes.

Predicting complex organism-level phenotypes—such as disease susceptibility in humans, bioproduction efficiency and optimal growth conditions in animals, and treatment resistance in pathogens—is a fundamental challenge in genetics. Leveraging our unique DNA LM with genome-scale context capabilities, we aim to build an infrastructure that enables direct inference of organism-level phenotypes from genomic data. This innovation has the potential to revolutionize personalized medicine, agricultural advancements, and biotech applications.

CONTACT

create your own block from scratch